Functional Impact of Neurogenesis on Adult Learning and Memory

UoN-UK-C-M.Black [Converted]



Functional Impact of Neurogenesis on Adult Learning and Memory

This position is closed.

ESR11:  Functional impact of neurogenesis on adult learning and memory

Supervisor:   Kevin Fone
Host institution:   The University of Nottingham
Duration:  36 months.

Applications are invited for the above post to work with Prof Kevin Fone on a European funded project entitled ‘Functional impact of neurogenesis on adult learning and memory’ at the University of Nottingham. The successful candidate will register for a 3 year PhD in the School of Life Sciences. They will 1) perform behavioural and radiotelemetry studies to evaluate changes in a neurodevelopmental rodent model of depression, 2) utilise immunohistochemical techniques and confocal microscopy to characterise accompanying changes in hippocampal neurogenesis, and 3) examine the ability of novel compounds (e.g. inhibitors of NMDA receptor mediated signalling) to reverse the observed deficits.

Our research group has an established track record in the development and validation of animal models of CNS disorders using a combination of in vivo neuroscience techniques and the project will provide comprehensive skills and training and enable the successful candidate to embark on a career in neuroscience and drug discovery.

The project will be jointly supervised by Professor Kevin Fone, Dr Maddy King, and Dr Peter Wigmore
(Neuroscience group)

Successful candidates should have an excellent degree in Neuroscience, Pharmacology, Physiology or a related discipline and experience working with animals.  Applicants must also meet the Marie Curie Early Stage Researcher eligibility criteria (i.e. have no more than four years of research experience since obtaining their first degree) and MUST NOT have resided in the UK for more than 12 months in the last 3 years prior to their appointment.

UNOTT combinedImages from left: radiotelemetry, conditioned emotional response, Ki67 immunohistochemistry and structural MRI.